个人简介

   主要从事植物化学和药用植物功能成分发掘与资源利用相关的科研与教学工作。获得包括五项国家自然基金面上项目等科研课题二十余项，发表SCI论文五十余篇，获授权发明专利22件。目前任专业期刊《Nat Prod Bioprospect》编委，并为多个SCI期刊评议审稿人。

承担主要科研项目：

1. 广东省自然科学基金项目，银合欢豆荚和叶中潜在功能活性成分发掘研究（项目编号：2023A1515012805），2023.1-2025.12，主持。

2. 国家自然科学基金面上项目，青钱柳叶中潜在活性成分的诱导发掘及主要活性成分的结构衍化生成机制（32170401），2022.1-2025.12，主持。

3. 广东省自然科学基金项目，入侵植物阔叶丰花草潜在抗MRSA等功能活性成分发掘研究（项目编号：2019A1515011236），2019.10.1-2022.9.30，主持。

4. 广东省自然科学基金项目，南美蟛蜞菊潜在活性成分的诱导发掘研究（项目编号：2014A030313742），2019.1-2021.1，主持。

5. 国家自然科学基金面上项目，三叶木通潜在活性成分的诱导发掘及诱导机制研究（31470422），2015.1-2018.12，主持。

6. 广东省自然科学基金项目，南美蟛蜞菊潜在活性成分的诱导发掘研究（项目编号：2014A030313742），2015.1-2018.1，主持。

7. 国家自然科学基金面上项目，三种入侵植物潜在活性成分的诱导发掘及类冠酮素诱导剂的结构优化研究（31270406），2013.1-2016.12，主持。

8. 国家自然科学基金面上项目，紫茎泽兰调控其活性物质分泌的信号机制研究（30970453），2010.1-2012.12，主持。

9. 中科院知识创新工程重要方向项目，植物活性成分生物合成的诱导及信号调控（KSCX2-YW-Z-0804），2009.1-2011.12，主持。

10. 国家自然科学基金面上项目，活性JA类似物合成筛选及对药用植物有效成分的诱导研究（30870248），2009.1-2011.12，主持。

代表性论文：

1) Li-Mei Dong, Qiao-Lin Xu, Shao-Bo Liu, Shan-Xuan Zhang, Meng-Fei Liu, Jin-Long Duan, Jin-Kui Ouyang, Jia-Tao Hu, Fen-Yu Fu and Jian-Wen Tan*（通讯作者）. Germacrane sesquiterpene dilactones from Mikania micrantha and their antibacterial and cytotoxic activity. Molecules, 2023, 28(5), 2119. 

2) Tao Lou, Qiao-Lin Xu, Yu-Ling Tan, Shao-Bo Liu, Shan-Xuan Zhang, Ying Zeng, Feng-Qiang Jiang, and Jian-Wen Tan*（通讯作者）. Two new germacrane sesquiterpenoids from the inflorescences of Mikania micrantha. Phytochemistry Letters, 2023, 54: 141-145. 

3) Shao-Bo Liu, Lei Zeng, Qiao-Lin Xu*, Ying-Le Chen, Tao Lou, Shan-Xuan Zhang, and Jian-Wen Tan*（通讯作者）. Polycyclic phenol derivatives from the leaves of Spermacoce latifolia and their antibacterial and α-glucosidase inhibitory activity. Molecules, 2022, 27(10), 3334. 

4) Hui Ren, Shao-Bo Liu, Tao Lou, Fen-Yu Fu, Qiao-Lin Xu*, Shan-Xuan Zhang, and Jian-Wen Tan*（通讯作者）. Two new ent-kaurane diterpenoids from the leaves of Sphagneticola trilobata. Phytochemistry Letters, 2022, 49: 177-181. 

5) Mei Zhang, Jin-Kui Ouyang, Qiao-Lin Xu*, Shao-Bo Liu, Tao Qian, Li-Mei Dong, and Jian-Wen Tan*（通讯作者）. Thymol derivatives with antibacterial and cytotoxic activity from the aerial parts of Ageratina adenophora. RSC Advances, 2021, 11(10): 5755-5761. 

6) Jin-Kui Ouyang^#, Li-Mei Dong^#, Qiao-Lin Xu*, Jing Wang, Shao-Bo Liu, Tao Qian, Yun-Fei Yuan, Jian-Wen Tan*（通讯作者）. Triterpenoids with α-glucosidase inhibitory activity and cytotoxic activity from the leaves of Akebia trifoliata. RSC Advances, 2018, 8: 40483-40489. 

7) Bi Luo, Li-Mei Dong, Qiao-Lin Xu*, Qiang Zhang, Wen-Bin Liu, Xiao-Yi Wei, Xu Zhang, Jian-Wen Tan*（通讯作者）. Characterization and immunological activity of polysaccharides from Ixeris polycephala. International Journal of Biological Macromolecules, 2018, 113: 804-812.

8) Li-Mei Dong, Li-Lan Huang, Hang Dai, Qiao-Lin Xu, Jin-Kui Ouyang, Xu-Chao Jia, Wen-Xiang Gu*, Jian-Wen Tan*（通讯作者）. Anti-MRSA sesquiterpenes from the semi-mangrove Plant Myoporum Bontioides A. Gray. Marine Drugs, 2018, 16(11): 438.

9) Jin-Kui Ouyang, Li-Mei Dong, Qiao-Lin Xu*, Jing Wang, Shao-Bo Liu, Tao Qian, Yun-Fei Yuan, Jian-Wen Tan*（通讯作者）. Triterpenoids with α-glucosidase inhibitory activity and cytotoxic activity from the leaves of Akebia trifoliata. RSC Advances, 2018, 8: 40483-40489.

10) Qiang Zhang, Qiao-Lin Xu*, Xiao-Mei Xia, Li-Mei Dong, Bi Luo, Wen-Bin Liu, Jian-Wen Tan*（通讯作者）. A new phenylpropane-pimarane heterodimer and a new ent-kaurene diterpene from the husks of Oryza sativa. Phytochemistry Letters, 2018, 24: 120-124.

11) Bi Luo, Li-Mei Dong, Qiao-Lin Xu*, Xu Zhang, Qiang Zhang, Wen-Bin Liu, Jian-Wen Tan*（通讯作者）. A new monoterpene and a new sesquiterpene from the roots of Ageratina adenophora. Phytochemistry Letters, 2018, 24: 67-70.

12) Li-Mei Dong, Xu-Chao Jia, Qing-Wen Luo, Qiang Zhang, Bi Luo, Wen-Bin Liu, Xu Zhang, Qiao-Lin Xu*, Jian-Wen Tan*（通讯作者）. Phenolics from Mikania micrantha and their antioxidant activity. Molecules, 2017, 22(7), 1140.

13) Ying Luo, Hai-Yan Shen, Qing-Xiang Shen, Chao-Hui Cao, Min Zhang, Shi-Yin Long, Zong-Bao Wang, Jian-Wen Tan*（通讯作者）. A new anthraquinone and a new naphthoquinone from the whole plant of Spermacoce latifolia. Journal of Asian Natural Products Research, 2017, 19(9): 869-876

14) Li-Mei Dong, Xu-Chao Jia, Qing-Wen Luo, Yi-Ming Peng, Qiang Zhang, Bi Luo, Jian-Wen Tan*（通讯作者）. Four new ent-kaurene diterpene glucosides from Mikania micrantha. Phytochemistry Letters, 2017, 20: 155-159.

15) Li-Mei Dong, Mei Zhang, Qiao-Lin Xu, Qiang Zhang, Bi Luo, Qing-Wen Luo, Wen-Bin Liu, Jian-Wen Tan*（通讯作者）. Two new thymol derivatives from the Roots of Ageratina adenophora. Molecules, 2017, 22(4), 592.

16) Hui Ren, Qiao-Lin Xu, Mei Zhang, Li-Mei Dong, Qiang Zhang, Bi Luo, Qin-Wen Luo and Jian-Wen Tan*（通讯作者）. Bioactive caffeic acid derivatives from Wedelia trilobata. Phytochemistry Letters, 2017, 19: 18-22.

17) Qiao-Lin Xu, Jing Wang, Li-Mei Dong, Qiang Zhang, Bi Luo, Yong-Xia Jia, Hong-Feng Wang, and Jian-Wen Tan*（通讯作者）. Two new pentacyclic triterpene saponins from the leaves of Akebia trifoliata. Molecules, 2016, 21(7), 962.

18) Jing Wang, Hui Ren, Qiao-Lin Xu, Zhong-Yu Zhou, Ping Wu, Xiao-Yi Wei, Yong Cao, Xue-Xiang Chen and Jian-Wen Tan*（通讯作者）. Antibacterial oleanane-type triterpenoids from pericarps of Akebia trifoliata. Food Chemistry. 2015, 168: 623-629.

19) Hui Ren, Qiao-Lin Xu, Ying Luo, Mei Zhang, Zhong-Yu Zhou, Li-Mei Dong and Jian-Wen Tan*（通讯作者）. Two new ent-kaurane diterpenoids from Wedelia trilobata (L.) Hitchc. Phytochemistry Letters, 2015, 11: 260-263.

20) Meng-Fei Zheng, Hui Ren, Ying Luo, Li-Mei Dong, Ling-Qiong Wang, Zhong-Yu Zhou and Jian-Wen Tan*（通讯作者）. A new diantheramide and a new cyclic peptide from the seeds of Vaccaria hispanica. Phytochemistry Letters, 2015, 11: 240-244.

21) Ying Luo, Qiao-Lin Xu, Li-Mei Dong, Zhong-Yu Zhou, Yu-Chan Chen, Wei-Min Zhang, and Jian-Wen Tan*（通讯作者）. A new ursane and a new oleanane triterpene acids from the whole plant of Spermacoce latifolia. Phytochemistry Letters, 2015, 11: 127-131.

22) Jing Wang, Qiao-Lin Xu, Meng-Fei Zheng, Hui Ren, Ting Lei, Ping Wu, Zhong-Yu Zhou, Xiao-Yi Wei, and Jian-Wen Tan*（通讯作者）. Bioactive 30-noroleanane triterpenes from the pericarps of Akebia trifoliata. Molecules, 2014, 19(4): 4301-4312.

23) Qiao-Lin Xu, Mei Zhang, Zhong-Yu Zhou, Wan-Xue Liu, Fang-Hao Wan, Hong-Feng Wang and Jian-Wen Tan*（通讯作者）. Two new carene-type monoterpenes from aerial parts of Ageratina adenophora. Phytochemistry Letters, 2014, 9: 123-126.

24) Zhong-Yu Zhou, Wan-Xue Liu, Gang Pei, Hui Ren, Jing Wang, Qiao-Lin Xu, Hai-Hui Xie, Fang-Hao Wan, and Jian-Wen Tan*（通讯作者）. Phenolic compounds from Ageratina adenophora roots and their allelopathic effects on Arabidopsis seeds germination and seedling growth. Journal of Agricultural and Food Chemistry, 2013, 61(48): 111792-111799.

25) Mei Zhang, Wan-Xue Liu, Meng-Fei Zheng, Qiao-Lin Xu, Fang-Hao Wan, Jing Wang, Ting Lei, Zhong-Yu Zhou, and Jian-Wen Tan*（通讯作者）. Bioactive quinic acid derivatives from Ageratina adenophora. Molecules, 2013, 18(11): 14096-14104.

26) Jian Yan, Li-Rong Sun, Zhong-Yu Zhou, Yu-Chan Chen, Wei-Min Zhang, Hao-Fu Dai, and Jian-Wen Tan*（通讯作者）. Homoisoflavonoids from the medicinal plant Portulaca oleracea. Phytochemistry, 2012, 80: 37-41.

27) Jian Yan, Zhong-Yu Zhou, Mei Zhang, Jing Wang, Hao-Fu Dai, and Jian-Wen Tan*（通讯作者）. New serratene triterpenoids from Palhinhaea cernua and their cytotoxic activity. Planta Medica, 2012, 78(12): 1387-1391.

28) Mei Zhang, Zhong-Yu Zhou, Jing Wang, Yong Cao, Xue-Xiang Chen, Wei-Min Zhang, Li-Dong Lin, and Jian-Wen Tan*（通讯作者）. Phytoecdysteroids from the roots of Achyranthes bidentata Blume. Molecules, 2012, 17(3): 3324-3332.

发明专利：

1) 谭建文、刘少博、娄涛、张善炫、徐巧林，一种三萜二糖苷化合物的制备方法和在制备抗肿瘤药物中的应用，中国发明专利，专利号：202211065395.4 

2) 谭建文、罗碧、徐巧林、董丽梅，一种阿拉伯半乳聚糖KMCP及其制备方法和在制备免疫调节剂中的应用，中国发明专利，专利号：ZL201810158851.7 

3) 谭建文、徐巧林、欧阳锦逵、钱涛、刘少博，三叶木通降三萜化合物在制备糖苷酶抑制剂药物中的应用，中国发明专利，专利号：ZL202010941081.0

4) 谭建文、徐巧林、刘少博、钱涛，一种7-醛基-9-异丁酰氧基-8-羟基百里酚其在制备抗菌剂或抗菌药物中的应用，中国发明专利，专利号：ZL202011573124.0 

5) 谭建文、谷文祥、董丽梅、徐巧林，两种新生物碱及其制备方法和在制备抗MRSA的抗菌剂中的应用，中国发明专利，专利号：ZL201811308265.2 

6) 谭建文、钱涛、徐巧林、刘少博，一种自显齿蛇葡萄叶中方便快速提纯二氢杨梅素的方法，中国发明专利，专利号：ZL201911302588.5 

7) 谭建文、徐巧林、王晶、任慧、郑梦斐，一种植物防御诱导剂冠酮甘素及其制备方法和用途，中国发明专利，专利号：ZL201310059183.X

8) 谭建文、王晶、郑梦斐、周忠玉、董丽梅，3α-羟基-30-齐墩果-12,20(29)-二烯-28-酸的制备方法和在制备抗肿瘤药物中的应用，中国发明专利，专利号：ZL201310648287.4

9) 谭建文、任慧、周忠玉、徐巧林，一种咖啡酰对羟基苯酚酯及其制备方法和在制备酪氨酸酶抑制剂中的应用，中国发明专利，专利号：ZL201510058731.6 

10) 谭建文、王晶、徐巧林、董丽梅、罗碧，一种三萜化合物在制备糖苷酶抑制剂药物中的应用，中国发明专利，专利号：ZL201610578627.4

奖励荣誉：

2008年获中国科学院‘百人计划’项目支持

承担主要课程：

《森林植物资源开发与利用》、《中药化学》、《专业导论》等